CBG (Cannabigerol): A Lesser-Known but Important Cannabinoid
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CBG (Cannabigerol) is a less-known cannabinoid in the cannabis plant but it is the critical agent for producing other cannabinoids e.g., THC and CBD. Known also as the "mother" or "stem" cell cannabinoid, CBG is found at lower levels than THC and CBD in most cannabis cultivars. However, its distinctive features and possible therapeutic values have attracted the growing attention of researchers as well as cannabis users.
What is CBG?
CBG is a non-psychoactive cannabinoid, meaning it does not produce the "high" typically associated with THC. It is principally identified during in the early stages of cannabis plant development when it is transformed into other cannabinoids like THC, CBD and CBC (Cannabichromene) as the plant develops.
Because cannabis strains are typically bred for higher concentrations of THC and CBD, CBG levels are generally lower, but selective breeding techniques are now being used to produce strains with higher levels of CBG.
CBG has been shown to affect the body's endocannabinoid system, specifically the CB1 and CB2 receptors, although this action remains to be thoroughly elucidated.
Potential Benefits of CBG
Although CBG research is still at the earliest stage, the results indicate that it has a good therapeutic value in many diseases. Some of the key benefits attributed to CBG include:
- Anti-Inflammatory Properties: CBG has also been shown to possess potent anti-inflammatory properties potentially useful for inflammatory diseases such as disease as inflammatory bowel disease (IBD), Crohn's disease, and arthritis.
- Neuroprotective Effects: Preliminary studies suggest that CBG may help protect brain cells and improve cognitive function, making it a potential candidate for the treatment of neurodegenerative diseases like Alzheimer's and Parkinson’s.
- Antibacterial and Antifungal: CBG has previously been shown to have antibacterial and antifungal activities, especially against drug-resistant bacteria such as MRSA (Methicillin-resistant Staphylococcus aureus), so CBG may be useful in the context of an antimicrobial treatment.
- Appetite Stimulation: Similar to THC, CBG may help stimulate appetite, which could be useful for individuals experiencing appetite loss due to conditions like cancer, HIV/AIDS, or chemotherapy treatments.
- Glaucoma Treatment: There are a few studies indicating CBG can contribute to lower intraocular pressure, and CBG could be used to treat glaucoma.
CBG vs. CBD and THC
Although both CBD and THC are widely recognized as cannabinoids with dissimilar effects, CBG is different from the two in a number of respects. As is the case with CBD, CBG is non-psychoactive--i.e., it does not produce, or cause, an elevated (high) mood. On the other hand, CBG has a different mode of interaction with the body.
Although CBD exerts a main effect through the serotonin and vanilloid receptors to alleviate anxiety and inflammation, CBG seems to exert a wider spectrum of putative benefits, working on the CB1 and CB2 receptors, and modulating other systems from the inside out.
Additionally, CBG’s ability to stimulate appetite and its neuroprotective properties set it apart from both THC and CBD, offering a distinct range of potential therapeutic uses.
The Future of CBG
As research into CBG continues to grow, it is becoming increasingly recognized for its potential health benefits. Although CBG is yet another cannabinoid that is still quite rare in most cannabis strains, breeders are working towards the creation of CBG-enriched strains that become relatively more easily available to consumers searching for its unique benefits.
Products containing CBG, such as oils, tinctures, and topical, are now starting to appear on the market offering persons the opportunity to experience its therapeutic applications.
Conclusion
CBG (Cannabigerol) is a less-well-known, but clinically significant cannabinoid with considerable promise in the cannabis-based world. Although research is at an early stage, CBG has been shown to possess anti-inflammatory, neuroprotective, and antimicrobial activities, which hold the potential to serve as a therapeutic candidate for a wide range of diseases.
With the increasing development of the cannabis industry and the breeding of cannabis strains with increasingly high content of CBG, CBG is expected to play an important role in both medical and wellness fields.